Changes

== Acid-Base Balance ==

== Acid-Base Balance ==

When we talk about acid-base balance, we are referring to the pH balance (degree of acidity or alkalinity) of substances or of the body. The symbol pH is used after numbers that measure the degree of the acidity or alkalinity of solutions. The acidity or the alka- linity of a solution is determined by the number of hydrogen ions (H + ) it contains. The smaller the pH value of a solution; that is, the smaller the number preceding the symbol pH is, the greater is the acidity of that solution. Likewise, the larger the number in front of the symbol pH is, the greater is the alkalinity of the solution.

When we talk about acid-base balance, we are referring to the pH balance (degree of acidity or alkalinity) of substances or of the body. The symbol pH is used after numbers that measure the degree of the acidity or alkalinity of solutions. The acidity or the alkalinity of a solution is determined by the number of hydrogen ions (H + ) it contains. The smaller the pH value of a solution; that is, the smaller the number preceding the symbol pH is, the greater is the acidity of that solution. Likewise, the larger the number in front of the symbol pH is, the greater is the alkalinity of the solution.

Any neutral solution, such as water, will have a pH value of 7.0. Solutions which have a pH value below 7.0 are acidic in nature. Solutions which have a pH value above 7.0 are considered to be alkaline, or basic.

Any neutral solution, such as water, will have a pH value of 7.0. Solutions which have a pH value below 7.0 are acidic in nature. Solutions which have a pH value above 7.0 are considered to be alkaline, or basic.

|Pancreatic Juices 8.0

|Pancreatic Juices 8.0

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The blood is slightly alkaline, with a pH of 7.35 to 7.4. Many of the enzymes that facilitate metabolic reactions operate optimally only in solutions of specific alkalinity. When there is a deviation from this level of alkalinity, whether higher (referred to as alkalosis), or lower (referred to as acidosis), severe malfunctions can occur. These mal- functions are manifested by slower enzymatic reactions, and thus a decrease in synthesis

The blood is slightly alkaline, with a pH of 7.35 to 7.4. Many of the enzymes that facilitate metabolic reactions operate optimally only in solutions of specific alkalinity. When there is a deviation from this level of alkalinity, whether higher (referred to as alkalosis), or lower (referred to as acidosis), severe malfunctions can occur. These malfunctions are manifested by slower enzymatic reactions, and thus a decrease in synthesis of specialized molecules, such as vitamins, proteins, etc. There is also an impairment of the production of ATP molecules that are needed for energy and are made from glucose. The major effect of acidosis is disorientation due to the depression of the central nervous system. Inversely, the major effect of alkalosis is extreme nervousness, eventually leading to convulsive reactions, namely tonic spasm. This spasm is referred to as tetany, and usually develops primarily in the musculature of the forearm and face, then spreads over the muscular system of the entire body. Tetany results from over-excitability of the central and peripheral nervous systems due to alkalosis.

 

of specialized molecules, such as vitamins, proteins, etc. There is also an impairment of the production of ATP molecules that are needed for energy and are made from glucose. The major effect of acidosis is disorientation due to the depression of the central ner- vous system. Inversely, the major effect of alkalosis is extreme nervousness, eventually leading to convulsive reactions, namely tonic spasm. This spasm is referred to as tetany, and usually develops primarily in the musculature of the forearm and face, then spreads over the muscular system of the entire body. Tetany results from over-excitability of the

 

central and peripheral nervous systems due to alkalosis.

== Body Maintenance Of Normal pH ==

== Body Maintenance Of Normal pH ==

In order to maintain a proper pH in the bodily fluids, and so that acidosis or alkalosis will not manifest, three major physiological control systems exist within the body. The first mechanism involves a buffer system for the hydrogen ion fluctuations. All bodily fluids are supplied with acid-base buffers which combine with any acid or alkaline sub- stance and prevent excessive change in the hydrogen ion concentration.

In order to maintain a proper pH in the bodily fluids, and so that acidosis or alkalosis will not manifest, three major physiological control systems exist within the body. The first mechanism involves a buffer system for the hydrogen ion fluctuations. All bodily fluids are supplied with acid-base buffers which combine with any acid or alkaline sub- stance and prevent excessive change in the hydrogen ion concentration.

Another mechanism the body uses to maintain normal pH is within the respiratory system. When the hydrogen ion concentration (H + ) changes measurably, the respiratory system is immediately stimulated to alter the rate of pulminary ventilation. This brings about a change in the quantity of carbon dioxide (CO2) within the system. High levels of carbon dioxide in the system, as created when holding the breath or due to physiolog- ical impairments of respiration, increase the acidity of the bloodstream. Any disease that interferes with normal breathing, such as emphysema or asthma, will impede the release of CO2 from the lungs and, subsequently, this CO2 will combine with water to form car- bonic acid. This increases the concentration of hydrogen ions, and thus the acidity of the blood is simultaneously increased.

Another mechanism the body uses to maintain normal pH is within the respiratory system. When the hydrogen ion concentration (H + ) changes measurably, the respiratory system is immediately stimulated to alter the rate of pulmonary ventilation. This brings about a change in the quantity of carbon dioxide (CO2) within the system. High levels of carbon dioxide in the system, as created when holding the breath or due to physiological impairments of respiration, increase the acidity of the bloodstream. Any disease that interferes with normal breathing, such as emphysema or asthma, will impede the release of CO2 from the lungs and, subsequently, this CO2 will combine with water to form carbonic acid. This increases the concentration of hydrogen ions, and thus the acidity of the blood is simultaneously increased.

The last of the three major physiological control systems of the body to maintain nor- mal pH involves the kidneys. When the (H + ) (hydrogen concentration) deviates from a normal value, the kidneys excrete either an acid or alkaline urine. This serves to help readjust the (H + ) of the bodily fluids back toward the normal value.

The last of the three major physiological control systems of the body to maintain normal pH involves the kidneys. When the (H + ) (hydrogen concentration) deviates from a normal value, the kidneys excrete either an acid or alkaline urine. This serves to help readjust the (H + ) of the bodily fluids back toward the normal value.

The key point to keep in mind when you are trying to understand the terms acidosis and alkalosis is that, as was previously mentioned, when the hydrogen ion concentration (H + ) is above normal, there is a state of acidosis and when the (H + ) falls below normal, we have alkalosis. If either acidosis or alkalosis occur within the bodily fluids, the buffer systems; namely, the lungs and kidneys, the organs that influence the accep- tance or excretion of hydrogen ions, will attempt to regulate the imbalance. In a normal, healthy individual, any increase or decrease in (H + ) will be modified so that the pH of the blood does not fluctuate from its normal range of 7.35 to 7.45. If, however, either the lungs or kidneys fail to function properly, the end result is often acidosis or alkalosis.

The key point to keep in mind when you are trying to understand the terms acidosis and alkalosis is that, as was previously mentioned, when the hydrogen ion concentration (H + ) is above normal, there is a state of acidosis and when the (H + ) falls below normal, we have alkalosis. If either acidosis or alkalosis occur within the bodily fluids, the buffer systems; namely, the lungs and kidneys, the organs that influence the acceptance or excretion of hydrogen ions, will attempt to regulate the imbalance. In a normal, healthy individual, any increase or decrease in (H + ) will be modified so that the pH of the blood does not fluctuate from its normal range of 7.35 to 7.45. If, however, either the lungs or kidneys fail to function properly, the end result is often acidosis or alkalosis.

Acidosis and alkalosis both have numerous causes. As mentioned above, one or more of the body’s buffer systems may be impaired in some way. Thus, acidosis or alka- losis may occur. Also, acidosis or alkalosis may result because of improper respiration (breathing), improper diet or both.

Acidosis and alkalosis both have numerous causes. As mentioned above, one or more of the body’s buffer systems may be impaired in some way. Thus, acidosis or alkalosis may occur. Also, acidosis or alkalosis may result because of improper respiration (breathing), improper diet or both.

An example of respiratory alkalosis is when a person ascends to a very high altitude and proceeds to overbreathe because he is aware of the low oxygen content in the air. This overbreathing results in an excessive loss of CO2, referred to as a mild state of res- piratory alkalosis. If such a situation persists and the individual fails to acclimate, even- tually the balance of acid and alkalinity in the blood may be altered.

An example of respiratory alkalosis is when a person ascends to a very high altitude and proceeds to over-breathe because he is aware of the low oxygen content in the air. This over-breathing results in an excessive loss of CO2, referred to as a mild state of respiratory alkalosis. If such a situation persists and the individual fails to acclimate, eventually the balance of acid and alkalinity in the blood may be altered.

Both diarrhea and vomiting are considered to be some common causes of metabolic acidosis. During diarrhea, large amounts of sodium bicarbonate, an alkaline substance, are secreted from the gastrointestinal tract; and during vomiting, there is a loss of alka- line substances deep within the gastrointestinal tract.

Both diarrhea and vomiting are considered to be some common causes of metabolic acidosis. During diarrhea, large amounts of sodium bicarbonate, an alkaline substance, are secreted from the gastrointestinal tract; and during vomiting, there is a loss of alkaline substances deep within the gastrointestinal tract.

However, diarrhea and vomiting are processes the body uses to speedily eliminate highly toxic materials from the body so these toxins cannot harm the tissues. Diarrhea and vomiting are not themselves causes of acidosis. Rather, they result from the same offending substance(s) that the acidosis results from.

However, diarrhea and vomiting are processes the body uses to speedily eliminate highly toxic materials from the body so these toxins cannot harm the tissues. Diarrhea and vomiting are not themselves causes of acidosis. Rather, they result from the same offending substance(s) that the acidosis results from.

# Exhalation or retention of CO2 by the lungs.

# Exhalation or retention of CO2 by the lungs.

# Metabolic production of acids by the tissues.

# Metabolic production of acids by the tissues.

# Concentration of proteins in the blood.  We have already discussed briefly these first two mechanisms. In order to understand the latter two, we must begin our study of dietary influences upon the body’s acidity and alkalinity.

# Concentration of proteins in the blood.   

We have already discussed briefly these first two mechanisms. In order to understand the latter two, we must begin our study of dietary influences upon the body’s acidity and alkalinity.

== Acid And Alkaline In The Diet ==

== Acid And Alkaline In The Diet ==